Manoj Gopalakrishnan

Assistant Professor
Department of Physics
Indian Institute of Technology Madras
Chennai 600036
TEL: +91-44-22574894 (O), 6894(R)
 Office : HSB224
Email: manojATphysics.iitm.ac.in, manojgopalATiitm.ac.in

 

Current Research Interests

I am engaged in quantitative modeling of biophysical processes, i.e., using physics and mathematics to understand how a cell works! At the moment, I am mostly focused on the following areas, but this list would, for sure keep changing with time.

Cell Motility
Signal Transduction
Motor protein based transport
Cytoskeletal filament kinetics

My CV is here

Ph.D students/post-docs interested in working in Theoretical Biophysics are welcome to get in touch with me. .

Teaching

Quantum Mechanics (EP 221, Aug-Dec 2009, IIT Madras)
Mathematical Methods (Aug-Dec 2008, HRI Graduate School)
Statistical Physics (Jan-May 2007, HRI Graduate School)

Recent publications

Optimization strategies of chromosome search-and-capture by microtubules: exact analytical results for a single fixed target, M. Gopalakrishnan and B. S. Govindan ( arxiv: 0904.0111, 2009 under review)

From random to directed motion: Understanding chemotaxis in E.Coli within a simplified model, M. Reneaux and M. Gopalakrishnan ( arxiv: 0812.4583, 2009, submitted to proceedings of IPCMB2008, Kolkata)

Length control of microtubules by depolymerizing molecular motors, B. S. Govindan, M. Gopalakrishnan and D. Chowdhury, EPL 83, 40006 (2008)

Self-consistent theory of reversible ligand binding to a spherical cell surface, S. Ghosh, M. Gopalakrishnan and K. Forsten-Williams, Phys. Biol. 4(4) 344-354 (2007)

Response and fluctuations of a two-state signaling module with feedback, M. Gopalakrishnan, P. Borowski, F. Julicher and M. Zapotocky, Phys. Rev. E 76 021904-921 (2007)

Effect of receptor coupling on ligand dissociation: Theory and simulations, M. Gopalakrishnan, K. Forsten-Williams, M. A. Nugent and U. C. Tauber, Biophys. J 89 3686-3700 (2005)

Ligand dissociation: Self-consistent mean-field theory and numerical simulations applied to SPR studies, M. Gopalakrishnan, K. Forsten-Williams, T. R. Cassino, L. Pedro, T. E. Ryan and U. C. Tauber, Eur.Biophys. J. 34 943-958(2005)

Complete list of Publications